Early- and late-state subacute sclerosing panencephalitis: chemical shift imaging and single-voxel MR spectroscopy.

Proton MR spectroscopy in the diagnosis of early-stage subacute sclerosing panencephalitis.

Subacute sclerosing panencephalitis (SSPE) is a progressive, fatal neurological disorder of childhood and early adolescence. In this report, we present brain magnetic resonance spectroscopy (MRS) and conventional magnetic resonance MR imaging findings of early-stage (stage II) SSPE in an 8-year-old child. MRS demonstrated increased myo-inositol/creatine and choline/creatine ratios, and a decrea...

MR imaging vs CT in subacute sclerosing panencephalitis.

The MR findings in three patients with subacute sclerosing panencephalitis were reviewed and compared with CT findings in the same patients. Long-T2 lesions were demonstrated in each case, although their distribution varied with the clinical stage of the disease. MR, especially T2-weighted imaging, appears to be of great utility in the assessment of subacute sclerosing panencephalitis.

Subacute sclerosing panencephalitis findings at MR imaging, diffusion MR imaging, and proton MR spectroscopy.

A case of subacute sclerosing panencephalitis in a 2-year-old boy is reported. In addition to asymmetric lesions in the parietotemporal lobes, right thalamus, and globus pallidus, symmetric patterns were notable in the brain stem, middle cerebellar pedincles, and dentate nuclei. Proton MR spectroscopy revealed markedly decreased N-acetylaspartate peaks and normal choline and myo-inositol levels...

Subacute Sclerosing Panencephalitis, immunological findings in saliva and salivary glands

Reduced gray matter volume in the frontotemporal cortex of patients with early subacute sclerosing panencephalitis.

BACKGROUND AND PURPOSE Subacute sclerosing panencephalitis (SSPE) is a persistent infection of the central nervous system by the measles virus. Patients in the initial stages of SSPE show behavioral symptoms and usually normal cranial MR imaging findings. We aimed to investigate the gray matter volume changes in patients with early SSPE. MATERIALS AND METHODS Seventeen patients with SSPE with...